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2001: Klempner's retreatment study in which 2/3 of the participants had not received prior treatment.
Mark Klempner’s 2001 long-term treatment study (90 days total) had a number of flaws and yet is upheld as "proof" that antibiotics are not beneficial to patients with "chronic Lyme".
There were never enough participants; he used invalid methods; he found "no DNA-positive patients" among the previously treated because he threw the DNA positive victims out of the study. Two-thirds of the patients had never been treated before; he never reported what primers he used; and no scientifically valid assessments of outcomes of this standard of care "study" were performed.
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This became the essence of the IDSA "guidelines," whereas ILADS is not aware or does not care that OspA alone caused the same post-sepsis outcome that we call "Chronic Lyme."
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